The distance is 2396 kilometers in a straight line. Route from Zhengzhou to Sanya: Zhengzhou → Zheng Shi Expressway → Yongdeng Expressway → Xupingnan Expressway → Beijing/Zhuhai → Beijing-Zhuhai Expressway → Shenzhen/Foshan/Dongguan/Zhaoqing/Beihuan Expressway → Huancheng Expressway → Guangfo Expressway/Zhaoqing/Lishui/Kaiping/Shabei/Beijiang levee → Fokai Expressway → Kaiyang Expressway → Yang Mao Expressway → Maozhan Expressway → Yuzhan Expressway. Nisha → 207 national highway → Xu Hai Road → Hongqi Second Road → 207 national highway/Xu Hai Road → Haigang Road → Binhai Avenue → Qiuhai Avenue → Nanhai Avenue → Hu Hongcheng Road → Qiongzhou Avenue → East Line Expressway → Yuya Avenue → National Highway 223 → Fenghuang Road → Xinfeng Street → Sanya.