It is not recommended to take a bus to go to Shamian at Guangzhou South Railway Station, but you can take the public transport —— Metro.
You follow the signs at Guangzhou South Railway Station, find the subway entrance of Guangzhou South Railway Station, take Line 2 to Haizhu Square Station, transfer to Line 6 to Huangsha Station, and get off at Exit F.. Then walk over the footbridge, and you can get to Shamian European amorous feelings area.