Chemical deratization, also known as drug deratization, is a widely used and effective deratization method. Drug deratization can be divided into intestinal poison deratization and fumigation deratization. As an intestinal rodenticide, organic compounds are the main ones, followed by inorganic compounds, wild plants and their extracts. Gastrointestinal rodenticide requires good palatability to rats, will not refuse to eat, and has appropriate toxicity. It is mainly used to make various poison baits with good effect, simple usage and large dosage. Followed by poisonous water, poisonous powder, poisonous glue, poisonous foam and so on. Fumigation and deratization, such as aluminum phosphide and chloropicrin, can be used for fumigation and deratization in warehouses and ships.